منابع مشابه
Regioselective synthesis of 1,4-disubstituted imidazoles.
A short and efficient synthesis of 1,4-disubstituted imidazoles has been developed which provides the desired products with complete regioselectivity. This protocol allows preparation of compounds which are challenging to prepare by current literature methods in a regioselective fashion, a sterically and electronically diverse range of N-substituents being accessible. The sequence involves an u...
متن کاملSynthesis and biological screening of di- and trisubstituted imidazoles.
Disubstituted imidazoles were prepared by reacting appropriate phenylglyoxal with different aryl aldehydes in the presence of ammonium acetate. Trisubstituted imidazoles were prepared by reacting disubstituted imidazoles with chlorobenzene in the presence of catalytic amount of triethylamine (TEA). The synthesized compounds were characterized on the basis of IR, 1H-NMR and mass spectral data an...
متن کاملγ-Alumina Nanoparticle Catalyzed Efficient Synthesis of Highly Substituted Imidazoles.
γ-Alumina nano particle catalyzed multi component reaction of benzil, arylaldehyde and aryl amines afforded the highly substituted 1,2,4,5-tetraaryl imidazoles with good to excellent yield in less reaction time under the sonication as well as the conventional methods. Convenient operational simplicity, mild conditions and the reusability of catalyst were the other advantages of this developed p...
متن کاملSynthesis of a Brominated Biphenyl Chromium Tricarbonyl Complex
Hydroxycarbene complexes have been proposed as intermediates in industrial processes such as the Fischer-Tropsch process and hydroformylation. As part of the overall synthesis of an aryltethered version of a chromium hydroxycarbene complex we have examined three synthetic routes toward the brominated biphenyl chromium tricarbonyl compound (η-2’-bromobiphenyl)Cr(CO)3, which is an immediate precu...
متن کاملConverting oxazoles into imidazoles: new opportunities for diversity-oriented synthesis.
We report the optimization of a neglected reaction for the rapid and direct conversion of oxazoles into N-substituted imidazoles. The utility of this microwave-promoted reaction for diversity-oriented synthesis is demonstrated in the preparation of >40 N-substituted imidazoles, including α-imidazolyl esters.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1973
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.27-2179